Adventures of Superman (1987-2006) #591

Superman returns home after he apparently destroys Viroxx, but the virus strikes back at the thing he holds closest to his heart: Lois. Superman watches in horror as his wife is transformed into a mindless anti-body and is sent to claim more worlds for Viroxx.

Written By:
Marv Wolfman
Pencils:
Jose Franciso Medina Castillo
Inks:
Walden Wong
Cover By:
Comicraft, T. Horie, Dale Keown